Kladribin (Mavenclad®)
Sist oppdatert: Publisert:
Sist revidert av:Hanne Marie Bøe Lunde, spesialist i nevrologi
Kort om
Informasjonsmateriell
Effekt
Indikasjon
Kontraindikasjoner
Bivirkninger
Oppstart og rebehandling
Dosering
Overvåkning under behandling
Vaksinasjon
Bytte til og fra behandling med kladribin
Kilder
Referanser
- Giovannoni G, Comi G, Cook S, Rammohan K, Rieckmann P, Soelberg Sørensen P, Vermersch P, Chang P, Hamlett A, Musch B, Greenberg SJ; CLARITY Study Group. A placebo-controlled trial of oral cladribine for relapsing multiple sclerosis.N Engl J Med. 2010 Feb 4;362(5):416-26. PMID: 20089960 PubMed
- Giovannoni G, Soelberg Sorensen P, Cook S, Rammohan KW, Rieckmann P, Comi G, Dangond F, Hicking C, Vermersch P. Efficacy of Cladribine Tablets in high disease activity subgroups of patients with relapsing multiple sclerosis: A post hoc analysis of the CLARITY study. Mult Scler. 2018 Apr 1:1352458518771875. PMID: 29716436 PubMed
- Giovannoni G, Cook S, Rammohan K, Rieckmann P, Sørensen PS, Vermersch P, Hamlett A, Viglietta V, Greenberg S; CLARITY study group. Sustained disease-activity-free status in patients with relapsing-remitting multiple sclerosis treated with cladribine tablets in the CLARITY study: a post-hoc and subgroup analysis. Lancet Neurol. 2011 Apr;10(4):329-37. PMID: 21397565 PubMed
- Cook S, Vermersch P, Comi G, Giovannoni G, Rammohan K, Rieckmann P, Sørensen PS, Hamlett A, Miret M, Weiner J, Viglietta V, Musch B, Greenberg SJ; CLARITY Study Group. Safety and tolerability of cladribine tablets in multiple sclerosis: the CLARITY (CLAdRIbine Tablets treating multiple sclerosis orallY) study. Mult Scler. 2011 May;17(5):578-93. PMID: 21228029 PubMed
- Pakpoor J, Disanto G, Altmann DR, Pavitt S, Turner BP, Marta M, Juliusson G, Baker D, Chataway J, Schmierer K. No evidence for higher risk of cancer in patients with multiple sclerosis taking cladribine. Neurol Neuroimmunol Neuroinflamm. 2015 Oct 1;2(6):e158. PMID: 26468472 PubMed
- Hanne Marie Bøe Lunde, spesialist i nevrologi, PhD
- Øivind Fredvik Grytten Torkildsen, spesialist i nevrologi, professor PhD
- Unn Ljøstad, spesialist i nevrologi, professor PhD
- Åse Mygland, spesialist i nevrologi, professor dr med