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Dimetylfumarat (Tecfidera)

Sist revidert:
Sist revidert av:
  1. Gold R1, Kappos L, Arnold DL, Bar-Or A, Giovannoni G, Selmaj K, Tornatore C, Sweetser MT, Yang M, Sheikh SI, Dawson KT; DEFINE Study Investigators.. Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. N Engl J Med. 2012; 367(12): 1098-107. pmid:22992073 PubMed  
  2. Fox RJ1, Miller DH, Phillips JT, Hutchinson M, Havrdova E, Kita M, Yang M, Raghupathi K, Novas M, Sweetser MT, Viglietta V, Dawson KT; CONFIRM Study Investigators.. Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. N Engl J Med 2012; 20;367(12):: 1087-97. pmid:22992072 PubMed  
  3. Xu Z1, Zhang F, Sun F, Gu K, Dong S, He D.. Dimethyl fumarate for multiple sclerosis. Cochrane Database Syst Rev. 2015. pmid:25900414 PubMed  
  4. Rosenkranz T, Novas M, Terborg C.. PML in a Patient with Lymphocytopenia Treated with Dimethyl Fumarate. N Engl J Med 2015; 372: 1476-1478. pmid:25853765 PubMed  
  5. Nieuwkamp DJ1, Murk JL, van Oosten BW, Cremers CH, Killestein J, Viveen MC, Van Hecke W, Frijlink DW, Wattjes MP; PML in Dutch MS Patients Consortium.. PML in a patient without severe lymphocytopenia receiving dimethyl fumarate. N Engl J Med. 2015; Apr 9;372(15) : 1474-6. pmid:25853764 PubMed  
  6. van Oosten BW, Killestein J, Barkhof F, Polman CH, Wattjes MP.. PML in a patient treated with dimethyl fumarate from a compounding pharmacy. N Engl J Med. 2013; Apr 25;368(17): 1658-9. pmid:23614604 PubMed  
  7. Ermis U, Weis J, Schulz JB.. PML in a patient treated with fumaric acid. N Engl J Med. 2013 ; Apr 25;368(17): 1657-8.
  8. Sweetser MT, Dawson KT, Bozic C. Manufacturer's response to case reports of PML. N Engl J Med. 2013 ; Apr 25;368(17): 1659-61. pmid:23614605 PubMed  
  9. Gieselbach RJ, Muller-Hansma AH, Wijburg MT, de Bruin-Weller MS, van Oosten BW, Nieuwkamp DJ, Coenjaerts FE, Wattjes MP, Murk JL. Progressive multifocal leukoencephalopathy in patients treated with fumaric acid esters: a review of 19 cases.J Neurol. 2017 Jun;264(6):1155-1164. Erratum in: J Neurol. 2017 Jul 15;PMID: 28536921 PubMed  
  10. Longbrake EE, Naismith RT, Parks BJ, Wu GF, Cross AH.. 2. Dimethyl fumarate-associated lymphopenia: Risk factors and clinical significance.. Mult Scler J Exp Transl Clin. 2015 . pmid:26550483 PubMed  
  • Hanne Marie Bøe Lunde, spesialist i nevrologi, PhDØyvind Fredheim Torkildsen, spesialist i nevrologi, professor PhD
  • Lars Bø,spesialist i nevrologi, professor PhD
  • Unn Ljøstad, spesialist i nevrologi, professor PhD
  • Åse Mygland, spesialist i nevrologi, professor dr med