Hjerneinfarkt trombolyse
Sist revidert:
• European Stroke Organisation - guidelines: www.eso-stroke.org
• Helsedirektoratets retningslinjer for hjerneslag – 2018
• AHA/ASA 2018 Guidelines for the early management of patients with acute ischemic stroke 1
- Ole Morten Rønning, spesialist i nevrologi, professor dr med
- Åse Mygland, spesialist i nevrologi, professor dr med
- Unn Ljøstad, spesialist i nevrologi, professor PhD
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- Ma H, Campbell BCV, Parsons MW, Churilov L, Levi CR, Hsu C, Kleinig TJ, Wijeratne T, Curtze S, Dewey HM, Miteff F, Tsai CH, Lee JT, Phan TG, Mahant N, Sun MC, Krause M, Sturm J, Grimley R, Chen CH, Hu CJ, Wong AA, Field D, Sun Y, Barber PA, Sabet A, Jannes J, Jeng JS, Clissold B, Markus R, Lin CH, Lien LM, Bladin CF, Christensen S, Yassi N, Sharma G, Bivard A, Desmond PM, Yan B, Mitchell PJ, Thijs V, Carey L, Meretoja A, Davis SM, Donnan GA; EXTEND Investigators. Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke. N Engl J Med. 2019 May 9;380(19):1795-1803. PMID: 31067369.
- Campbell BCV1, Ma H2, Ringleb PA3, Parsons MW4, Churilov L5, Bendszus M6, Levi CR7, Hsu C8, Kleinig TJ9, Fatar M10, Leys D11, Molina C12, Wijeratne T13, Curtze S14, Dewey HM15, Barber PA16, Butcher KS17, De Silva DA18, Bladin CF19, Yassi N1, Pfaff JAR6, Sharma G4, Bivard A4, Desmond PM20, Schwab S21, Schellinger PD22, Yan B23, Mitchell PJ20, Serena J24, Toni D25, Thijs V26, Hacke W3, Davis SM4, Donnan GA27; EXTEND, ECASS-4, and EPITHET Investigators.. Extending thrombolysis to 4·5-9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data.. Lancet. 2019; Jul 13;394(10193):: 139-147. pmid:31128925 PubMed
- Dumitrascu OM, Shen JF, Kurli M, Aguilar MI, Marks LA, Demaerschalk BM, Wingerchuk DM, O'Carroll CB. Is Intravenous Thrombolysis Safe and Effective in Central Retinal Artery Occlusion? A Critically Appraised Topic. Neurologist. 2017 Jul;22(4):153-156. PMID: 28644261 PubMed
- Huang L, Wang Y, Zhang R. Intravenous thrombolysis in patients with central retinal artery occlusion: a systematic review and meta-analysis. J Neurol. 2022 Apr;269(4):1825-1833. PMID: 34625849. PubMed
- Thomalla G, Fiebach JB, Østergaard L, Pedraza S, Thijs V, Nighoghossian N, Roy P, Muir KW, Ebinger M, Cheng B, Galinovic I, Cho TH, Puig J, Boutitie F, Simonsen CZ, Endres M, Fiehler J, Gerloff C; WAKE-UP investigators. A multicenter, randomized, double-blind, placebo-controlled trial to test efficacy and safety of magnetic resonance imaging-based thrombolysis in wake-up stroke (WAKE-UP). Int J Stroke. 2014 Aug;9(6):829-36. PMID: 23490032 PubMed
- Thomalla G, Boutitie F, Fiebach JB, Simonsen CZ, Nighoghossian N, Pedraza S, Lemmens R, Roy P, Muir KW, Ebinger M, Ford I, Cheng B, Galinovic I, Cho TH, Puig J, Thijs V, Endres M, Fiehler J, Gerloff C; WAKE-UP Investigators. Stroke With Unknown Time of Symptom Onset: Baseline Clinical and Magnetic Resonance Imaging Data of the First Thousand Patients in WAKE-UP (Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke: A Randomized, Doubleblind, Placebo-Controlled Trial). Stroke. 2017 Mar;48(3):770-773. PMID: 28174327 PubMed
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- Logallo N, Novotny V, Assmus J, Kvistad CE, Alteheld L, Rønning OM, Thommessen B, Amthor KF, Ihle-Hansen H, Kurz M, Tobro H, Kaur K, Stankiewicz M, Carlsson M, Morsund Å, Idicula T, Aamodt AH, Lund C, Næss H, Waje-Andreassen U, Thomassen L. Tenecteplase versus alteplase for management of acute ischaemic stroke (NOR-TEST): a phase 3, randomised, open-label, blinded endpoint trial. Lancet Neurol. 2017 Oct;16(10):781-788. PMID: 28780236 PubMed
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- Naff N, Williams MA, Keyl PM, Tuhrim S, Bullock MR, Mayer SA, Coplin W, Narayan R, Haines S, Cruz-Flores S, Zuccarello M, Brock D, Awad I, Ziai WC, Marmarou A, Rhoney D, McBee N, Lane K, Hanley DF Jr. Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial. Stroke. 2011 Nov;42(11):3009-16. PMID: 21868730 PubMed
- Myslimi F, Caparros F, Dequatre-Ponchelle N, Moulin S, Gautier S, Girardie P, Cordonnier C, Bordet R, Leys D. Orolingual Angioedema During or After Thrombolysis for Cerebral Ischemia. Stroke. 2016 Jul;47(7):1825-30. PMID: 27197851 PubMed
- Alakbarzade V, O'Kane D, Pereira AC. Hypersensitivity reactions to recombinant tissue plasminogen activator. Pract Neurol. 2020 Feb;20(1):75-79. PMID: 31273082. PubMed
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- AVERT Trial Collaboration group. Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial. Lancet. 2015 Jul 4;386(9988):46-55. doi: 10.1016/S0140-6736(15)60690-0. Epub 2015 Apr 16. Erratum in: Lancet. 2015 Jul 4;386(9988):30. Erratum in: Lancet. 2017 May 13;389(10082):1884. PMID: 25892679 PubMed