Hopp til hovedinnhold

Restless Legs Syndrome RLS

Sist oppdatert: Sist revidert:
Sist revidert av:
  1. Trenkwalder C, Allen R, Högl B, Clemens S, Patton S, Schormair B, Winkelmann J. Comorbidities, treatment, and pathophysiology in restless legs syndrome. Comorbidities, treatment, and pathophysiology in restless legs syndrome. Lancet Neurol. 2018. pmid:30244828 PubMed  
  2. Winkelmann J, Allen RP, Högl B, Inoue Y, Oertel W, Salminen AV, Winkelman JW, Trenkwalder C, Sampaio C. Treatment of restless legs syndrome: Evidence-based review and implications for clinical practice (Revised 2017)§. Mov Disord. 2018 May 14. PMID: 29756335 PubMed  
  3. Picchietti DL, Bruni O, de Weerd A, Durmer JS, Kotagal S, Owens JA, Simakajornboon N; International Restless Legs Syndrome Study Group (IRLSSG). Pediatric restless legs syndrome diagnostic criteria: an update by the International Restless Legs Syndrome Study Group. Sleep Med. 2013 Dec;14(12):1253-9. PMID: 24184054 PubMed  
  4. Allen RP, Picchietti DL, Garcia-Borreguero D, Ondo WG, Walters AS, Winkelman JW, Zucconi M, Ferri R, Trenkwalder C, Lee HB; International Restless Legs Syndrome Study Group. Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance. Sleep Med. 2014 Aug;15(8):860-73. PMID: 25023924 PubMed  
  5. Garcia-Borreguero D, Silber MH, Winkelman JW, Högl B, Bainbridge J, Buchfuhrer M, Hadjigeorgiou G, Inoue Y, Manconi M, Oertel W, Ondo W, Winkelmann J, Allen RP. Guidelines for the first-line treatment of restless legs syndrome/Willis-Ekbom disease, prevention and treatment of dopaminergic augmentation: a combined task force of the IRLSSG, EURLSSG, and the RLS-foundation. Sleep Med. 2016 May;21:1-11. PMID: 27448465 PubMed  
  6. Ruppert E, Hacquard A, Tatu L, Namer IJ, Wolff V, Kremer S, Lagha-Boukbiza O, Bataillard M, Bourgin P. Stroke-related restless legs syndrome: Clinical and anatomo-functional characterization of an emerging entity. Eur J Neurol. 2022 Apr;29(4):1011-1016. doi: 10.1111/ene.15207. Epub 2021 Dec 23. PMID: 34889000. PubMed  
  7. Picchietti DL, Hensley JG, Bainbridge JL, Lee KA, Manconi M, McGregor JA, Silver RM, Trenkwalder C, Walters AS; International Restless Legs Syndrome Study Group (IRLSSG). Consensus clinical practice guidelines for the diagnosis and treatment of restless legs syndrome/Willis-Ekbom disease during pregnancy and lactation. Sleep Med Rev. 2015 Aug;22:64-77. PMID: 25553600 PubMed  
  8. García-Borreguero D1, Allen RP, Kohnen R, Högl B, Trenkwalder C, Oertel W, Hening WA, Paulus W, Rye D, Walters A, Winkelmann J, Earley CJ; International Restless Legs Syndrome Study Group. Diagnostic standards for dopaminergic augmentation of restless legs syndrome: report from a World Association of Sleep Medicine-International Restless Legs Syndrome Study Group consensus conference at the Max Planck Institute. Sleep Med. 2007 Aug;8(5):520-30. PMID: 17544323 PubMed  
  9. Garcia-Borreguero D, Cano-Pumarega I, Marulanda R. Management of treatment failure in restless legs syndrome (Willis-Ekbom disease). Sleep Med Rev. 2018 Jan 9. pii: S1087-0792(17)30114-4. PMID: 29602660 PubMed  
  10. Allen RP, Picchietti DL, Auerbach M, Cho YW, Connor JR, Earley CJ, Garcia-Borreguero D, Kotagal S, Manconi M, Ondo W, Ulfberg J, Winkelman JW; International Restless Legs Syndrome Study Group (IRLSSG). Evidence-based and consensus clinical practice guidelines for the iron treatment of restless legs syndrome/Willis-Ekbom disease in adults and children: an IRLSSG task force report. Sleep Med. 2018 Jan;41:27-44. PMID: 29425576 PubMed  
  11. Silber MH, Buchfuhrer MJ, Earley CJ, Koo BB, Manconi M, Winkelman JW; Scientific and Medical Advisory Board of the Restless Legs Syndrome Foundation. The Management of Restless Legs Syndrome: An Updated Algorithm. Mayo Clin Proc. 2021 Jul;96(7):1921-1937. PMID: 34218864. PubMed  
  12. Steensland I, Koskinen LD, Lindvall P. Treatment of restless legs syndrome with a pump; efficacy and complications. Acta Neurol Scand 2020. pmid:31883387 PubMed  
  13. Trotti LM, Bhadriraju S, Becker LA. Iron for restless legs syndrome. Cochrane Database Syst Rev. 2012 May 16;(5):CD007834. doi: 10.1002/14651858.CD007834.pub2. Review. Update in: Cochrane Database Syst Rev. 2019 Jan 04;1:CD007834. PMID: 22592724 PubMed  
  14. Bae H, Cho YW, Kim KT, Allen RP, Earley CJ. Randomized, placebo-controlled trial of ferric carboxymaltose in restless legs syndrome patients with iron deficiency anemia. Sleep Med. 2021 Aug;84:179-186. PMID: 34157632. PubMed  
  15. Tang M, Ge J, Sun KX, Cui B, Guan Y, Wang JW. A network meta-analysis of the effectiveness and safety of drugs for restless legs syndrome in dialysis patients. Semin Dial. 2021 Sep 28. PMID: 34585446. PubMed  
  16. Manconi M, Govoni V, De Vito A, Economou NT, Cesnik E, Casetta I et al. Restless legs syndrome and pregnancy. Neurology 2004;63:1065-9 Neurology  
  17. Hubner A, Krafft A, Gadient S, Werth E, Zimmermann R, Basetti CL. Characteristics and determinants of restless legs syndrome in pregnancy: a prospective study. Neurology 2013; 80:738-42 Neurology  
  • Michaela-Alexandra Dreetz Gjerstad, spesialist i nevrologi, PhD
  • Unn Ljøstad, spesialist i nevrologi, professor PhD
  • Åse Mygland, spesialist i nevrologi, professor dr med

Tidligere fagmedarbeidere

  • Einar Kinge, spesialist i nevrologi