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Vegetativ status og minimalt bevisst tilstand

Sist oppdatert: Sist revidert:
Sist revidert av:
  1. Medical aspects of the persistent vegetative state (1). The Multi-Society Task Force on PVS. N Engl J Med 1994; 330: 1499-508. New England Journal of Medicine  
  2. Giacino JT, Ashwal S, Childs N. The minimally conscious state: definition and diagnostic criteria. Neurology 2002; 58: 349-53. Neurology  
  3. Liberati G, Hünefeldt T, Olivetti Belardinelli M. Questioning the dichotomy between vegetative state and minimally conscious state: a review of the statistical evidence. Front Hum Neurosci. 2014 Nov 3;8:865 . pmid:25404905 PubMed  
  4. Bernat JL. Current controversies in states of chronic unconsciousness. Neurology 2010; 75: 33-8. Neurology  
  5. Norton L, Kazazian K, Gofton T, Debicki DB, Fernandez-Espejo D, Peelle JE, Al Thenayan E, Young GB, Owen AM. Functional neuroimaging as an assessment tool in critically ill patients. Ann Neurol. 2022 Oct 12. doi: 10.1002/ana.26530. Epub ahead of print. PMID: 36222470.
  6. Cruse D, Chennu S, Chatelle C, Bekinschtein TA, Fernández-Espejo D, Pickard JD, Laureys S, Owen AM.. Bedside detection of awareness in the vegetative state: a cohort study. Lancet 2011; 378(9809): 2088-94. pmid:22078855 PubMed  
  7. Koenig MA1, Kaplan PW.. Clinical Applications for EPs in the ICU.. J Clin Neurophysiol. 2016; 32(6): 472-80. pmid:26629757 PubMed  
  8. Hirschberg R, Giacino JT. The vegetative and minimally conscious States: diagnosis, prognosis and treatment. Neurol Clin 2011; 29: 773-86.
  9. Giacino JT, Whyte J, Bagiella E, Kalmar K, Childs N, Khademi A, Eifert B, Long D, Katz DI, Cho S, Yablon SA, Luther M, Hammond FM, Nordenbo A, Novak P, Mercer W, Maurer-Karattup P, Sherer M.. Placebo-controlled trial of amantadine for severe traumatic brain injury. N Engl J Med 2012; 366(9): 819-26. pmid:22375973 PubMed  
  10. Thibaut A, Bruno MA, Ledoux D, Demertzi A, Laureys S. tDCS in patients with disorders of consciousness: sham-controlled randomized double-blind study.. Neurology 2014 ; Apr 1;82(13): 1112-8. pmid:24574549 PubMed  
  11. O'Neal CM, Schroeder LN, Wells AA, Chen S, Stephens TM, Glenn CA, Conner AK. Patient Outcomes in Disorders of Consciousness Following Transcranial Magnetic Stimulation: A Systematic Review and Meta-Analysis of Individual Patient Data. Front Neurol. 2021 Aug 12;12:694970. PMID: 34475848 PubMed  
  12. Whyte J.. Disorders of consciousness: the changing landscape of treatment.. Neurology 2014; Apr 1;82(13): 1106-7. pmid:24574547 PubMed  
  13. Bender A, Jox RJ, Grill E, Straube A, Lulé D.. Persistent vegetative state and minimally conscious state: a systematic review and meta-analysis of diagnostic procedures. Dtsch Arztebl Int. 2015 Apr 3;112(14):235-42 . pmid: 25891806 PubMed  
  14. Baricich A, de Sire A, Antoniono E, Gozzerino F, Lamberti G, Cisari C, Invernizzi M. Recovery from vegetative state of patients with a severe brain injury:a 4-year real-practice prospective cohort study. Funct Neurol. 2017 Jul/Sep;32(3):131-136. pmid:29042001 PubMed  
  15. Illman NA, Crawford S. Late-recovery from "permanent" vegetative state in the context of severe traumatic brain injury: A case report exploring objective and subjective aspects of recovery and rehabilitation. Neuropsychol Rehabil. 2017 Apr 26:1-15 . pmid:28446065 PubMed  
  16. Willmott L, White B. Persistent vegetative state and minimally conscious state: ethical, legal and practical dilemmas. J Med Ethics. 2017 Jul;43(7):425-426. PMID: 28663409 PubMed  
  • Åse Mygland, spesialist i nevrologi, professor dr med
  • Unn Ljøstad, spesialist i nevrologi, professor, PhD