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Nevroborreliose

Sist oppdatert: Sist revidert:
Sist revidert av:
  1. Halperin JJ, Eikeland R, Branda JA, Dersch R. Lyme neuroborreliosis: known knowns, known unknowns. Brain. 2022 Aug 27;145(8):2635-2647. doi: 10.1093/brain/awac206. PMID: 35848861. PubMed  
  2. Ross Russell AL, Dryden M, Pinto AA, Lovett J. Lyme disease: diagnosis and management. Pract Neurol. 2018. pmid:30282764 PubMed  
  3. Mygland A, Ljøstad U, Fingerle V, Rupprecht T, Schmutzhard E, Steiner I. EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis. Eur J Neurol 2010; 17: 8-16. PMID: 19930447 PubMed  
  4. Cruickshank M, et al. Lyme disease: summary of NICE guidance. BMJ. 2018. pmid:29650513 PubMed  
  5. Lantos PM, Rumbaugh J, Bockenstedt LK, Falck-Ytter YT, Aguero-Rosenfeld ME, Auwaerter PG, Baldwin K, Bannuru RR, Belani KK, Bowie WR, Branda JA, Clifford DB, DiMario FJ Jr, Halperin JJ, Krause PJ, Lavergne V, Liang MH, Meissner HC, Nigrovic LE, Nocton JJJ, Osani MC, Pruitt AA, Rips J, Rosenfeld LE, Savoy ML, Sood SK, Steere AC, Strle F, Sundel R, Tsao J, Vaysbrot EE, Wormser GP, Zemel LS. Clinical Practice Guidelines by the Infectious Diseases Society of America, American Academy of Neurology, and American College of Rheumatology: 2020 Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease. Neurology. 2021 Feb 9;96(6):262-273. doi: 10.1212/WNL.0000000000011151. Epub 2020 Nov 30. Erratum in: Neurology. 2021 Feb 9;96(6):296. PMID: 33257476. PubMed  
  6. Eliassen KE, Reiso H, Berild D, Lindbæk M. Comparison of phenoxymethylpenicillin, amoxicillin, and doxycycline for erythema migrans in general practice. A randomized controlled trial with a 1-year follow-up. Clin Microbiol Infect. 2018 Dec;24(12):1290-1296. PMID: 29505880 PubMed  
  7. Ljøstad U, Mygland Å. Lyme-borreliose hos voksne. Tidsskr Nor Laegeforen 2008; 128: 1175-8. PMID: 18480867 PubMed  
  8. Eliassen KE, Berild D, Reiso H, Grude N, Christophersen KS, Finckenhagen C, Lindbæk M. Incidence and antibiotic treatment of erythema migrans in Norway 2005-2009. Ticks Tick Borne Dis. 2017 Jan;8(1):1-8. PMID: 27475874 PubMed  
  9. Stenør CPM, Mahdaoui SE, Wolfram N. Ultrasonic evidence of mononeuritis multiplex caused by Lyme neuroborreliosis. Muscle Nerve. 2022 Jan;65(1):E4-E6. PMID: 34644405. PubMed  
  10. Wittwer B, Pelletier S, Ducrocq X, Maillard L, Mione G, Richard S. Cerebrovascular Events in Lyme Neuroborreliosis. J Stroke Cerebrovasc Dis. 2015 Jul;24(7):1671-8 . pmid:26002071 PubMed  
  11. Rupprecht TA, Manz KM, Fingerle V, Lechner C, Klein M, Pfirrmann M, Koedel U. Diagnostic value of cerebrospinal fluid CXCL13 for acute Lyme neuroborreliosis. A systematic review and meta-analysis. Clin Microbiol Infect. 2018 Dec;24(12):1234-1240. doi: 10.1016/j.cmi.2018.04.007. Epub 2018 Apr 16. PMID: 29674128 PubMed  
  12. Lindland ES, Solheim AM, Andreassen S, Quist-Paulsen E, Eikeland R, Ljøstad U, Mygland Å, Elsais A, Nygaard GO, Lorentzen ÅR, Harbo HF, Beyer MK. Imaging in Lyme neuroborreliosis.. Imaging in Lyme neuroborreliosis. 2018; Oct;9(5): 833-844. pmid:30187265 PubMed  
  13. Garkowski A, Łebkowska U, Kubas B, Garkowska E, Rutka K, Gawarecka E, Zajkowska J. Imaging of Lyme Neuroborreliosis: A Pictorial Review. Open Forum Infect Dis. 2020 Aug 19;7(10):ofaa370. PMID: 33094114 PubMed  
  14. Ljøstad U, Henriksen TH. Management of neuroborreliosis in European adult patients. Acta Neurol Scand Suppl 2008;188: 22-8. PMID: 18439217 PubMed  
  15. Forselv KJN, Lorentzen ÅR, Ljøstad U, Mygland Å, Eikeland R, Kjelland V, Noraas S, Quarsten H. Does more favourable handling of the cerebrospinal fluid increase the diagnostic sensitivity of Borrelia burgdorferi sensu lato-specific PCR in Lyme neuroborreliosis? Infect Dis (Lond). 2018 Apr;50(4):297-302. PMID: 29125008 PubMed  
  16. van Gorkom T, Voet W, Sankatsing SUC, Nijhuis CDM, Ter Haak E, Kremer K, Thijsen SFT. Prospective comparison of two enzyme-linked immunosorbent spot assays for the diagnosis of Lyme neuroborreliosis. Clin Exp Immunol. 2019 Oct 30. PMID: 31665540 PubMed  
  17. Dersch R, Freitag MH, Schmidt S, Sommer H, Rauer S, Meerpohl JJ. Efficacy and safety of pharmacological treatments for acute Lyme neuroborreliosis - a systematic review. Eur J Neurol. 2015 Sep;22(9):1249-59 . pmid:26058321 PubMed  
  18. Solheim AM, Lorentzen ÅR, Dahlberg AO, Flemmen HØ, Brune S, Forselv KJN, Pripp AH, Bø MH, Eikeland R, Reiso H, Mygland Å, Ljøstad U. Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blinded, randomised and placebo-controlled trial. J Neurol Neurosurg Psychiatry. 2022 Jul 27;93(11):1222–8. doi: 10.1136/jnnp-2022-329724. Epub ahead of print. PMID: 35896378;
  19. Obel N, Dessau RB, Krogfelt KA, Bodilsen J, Andersen NS, Møller JK, Roed C, Omland LH, Christiansen CB, Ellermann-Eriksen S, Bangsborg JM, Hansen K, Benfield TL, Rothman KJ, Sørensen HT, Andersen CØ, Lebech AM.. Long term survival, health, social functioning, and education in patients with European Lyme neuroborreliosis: nationwide population based cohort study.. BMJ 2018. pmid:29848547 PubMed  
  20. Eikeland R, Ljøstad U, Mygland A, Herlofson K, Løhaugen GC.European neuroborreliosis: neuropsychological findings 30 months post-treatment.Eur J Neurol. 2012 Mar;19(3):480-7. doi: 10.1111/j.1468-1331.2011.03563.x. Epub 2011 Oct 15.PMID:21999112 PubMed  
  21. Dersch R, Sommer H, Rauer S, Meerpohl JJ. Prevalence and spectrum of residual symptoms in Lyme neuroborreliosis after pharmacological treatment: a systematic review. J Neurol. 2015 Oct 12 . pmid:26459093 PubMed  
  22. Dersch R, Sarnes AA, Maul M, Hottenrott T, Baumgartner A, Rauer S, Stich O. Quality of life, fatigue, depression and cognitive impairment in Lyme neuroborreliosis.. J Neurol. 2015 Sep 26 . pmid:26410742 PubMed  
  23. Berende A, ter Hofstede HJ, Vos FJ, van Middendorp H, Vogelaar ML, Tromp M, van den Hoogen FH, Donders AR, Evers AW, Kullberg BJ. Randomized Trial of Longer-Term Therapy for Symptoms Attributed to Lyme Disease. N Engl J Med. 2016 Mar 31;374(13):1209-20 . pmid: 27028911 PubMed  
  24. Berende A, Ter Hofstede HJM, Vos FJ, Vogelaar ML, van Middendorp H, Evers AWM, Kessels RPC, Kullberg BJ. Effect of prolonged antibiotic treatment on cognition in patients with Lyme borreliosis. Neurology. 2019 Mar 26;92(13):e1447-e1455. PMID: 30796143 PubMed  
  • Randi Eikeland, spesialist i nevrologi, PhD
  • Harald Reiso, spesialist i allmennmedisin, dr med
  • Unn Ljøstad, spesialist i nevrologi, professor PhD
  • Åse Mygland, spesialist i nevrologi, professor dr med